Continuous research and clinical studies

MIRTOGENOL^® – A first clinical study was performed with 20 patients (45.8 years) on Mirtogenol^® and 18 patients (44.7 years) who received placebo. Patients had moderately high intraocular pressure with average 25 mmHg, cup to disc ratio was more than 0.5 - ‘Initial/Minimal’ field of vision defects - and no medication was taken. Dose was 2 tablets Mirtogenol^® a day (80 mg Pycnogenol^®, 160 mg Mirtoselect^®) and treatment period was 3 months.

Supplementation with Mirtogenol^® significantly relieves high ocular pressure

Results showed that MIRTOGENOL^® lowered IOP in 19 of 20 patients, there was no effect on visual acuity, but an increased blood flow velocity in retinal and ciliary arteries (color Doppler imaging) and study was published in peer reviewed medical ophthalmology journal. A second MIRTOGENOL^® clinical study has now been completed, which investigated its effect on IOP at a lower dosage (1 tablet a day) . MIRTOGENOL^® was found to significantly improve IOP and maintain a healthier IOP over the six months investigational period. A significant increase ofocular blood flow was identified after taking MIRTOGENOL^®. Its effect on IOP was compared with prescribed medication eye drops containing Latanoprost in a parallel group as well as in combination with Latanoprost in a third group.  MIRTOGENOL^® was found to take longer to lower IOP than prescribed medication but is almost as effective as Latanoprost.

Taking Mirtogenol^® together with medication (Latanoprost) for intraocular hypertension is safe and aids to further normalize ocular pressure

MIRTOGENOL^® taken in addition to Latanoprost eye drops more effectively improves IOP. 

Systolic blood flow velocity [cm/s]

Diastolic blood flow velocity [cm/s]

MIRTOGENOL^® was equally effective for improving retinal blood flow, the combination with Latanoprost further improved retinal blood flow. In conclusion, taking MIRTOGENOL^® while using medications for IOP is safe and contributes to healthier IOP and better retinal blood flow. Unlike Latanoprost, MIRTOGENOL^® does not appear to have side effects.